Reye’s syndrome

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Reye’s syndrome
Classification and external resources
ICD–10	G93.7
ICD–9	331.81
DiseasesDB	11463
MedlinePlus	001565
eMedicine	emerg/399
MeSH	D012202

Reye’s syndrome is a potentially fatal disease that causes numerous detrimental effects to many organs, especially the brain and liver, as well as causing hypoglycemia.^[1] The exact cause is unknown, and while it has been associated with aspirin consumption by children with viral illness, it also occurs in the absence of aspirin use.
The disease causes fatty liver with minimal inflammation and severe encephalopathy (with swelling of the brain). The liver may become slightly enlarged and firm, and there is a change in the appearance of the kidneys. Jaundice is not usually present.^[2]
Early diagnosis is vital; while most children recover with supportive therapy, severe brain injury or death are potential complications.

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